Chicken Spinach and Mushroom Low-Carb Casserole

After a long day, nothing beats the comforting embrace of a warm casserole straight from the oven. Picture this: the delightful aroma of sautéed mushrooms mingling with fresh spinach and tender pieces of chicken fills your kitchen, promising a meal that warms both the belly and the soul. This Chicken Spinach and Mushroom Low-Carb Casserole isn’t just another weeknight dinner; it's a creamy, cheesy hug in a dish that even picky eaters will fall for.

As someone who loves creating meals that nurture without the guilt, I appreciate how this dish fits effortlessly into my busy life. With simple ingredients and straightforward steps, it transforms into a family favorite that's not only low-carb and gluten-free but also bursting with flavors that make every bite feel indulgent. Whether you’re prepping for a cozy family dinner or needing something quick to whip up for a gathering, this casserole has got you covered! Ready to dive in? Let’s get cooking!

Why Will You Love This Chicken Spinach and Mushroom Low-Carb Casserole?

Comforting Warmth: This casserole is like a warm embrace, featuring tender chicken, earthy mushrooms, and vibrant spinach that create a rich comfort food experience.

Easy to Make: With straightforward steps, even novice cooks can achieve this satisfying meal effortlessly, perfect for busy weeknights.

Flavor-Packed Layers: The combination of green onion cream cheese and mozzarella adds a creamy, cheesy indulgence that will impress everyone at the table.

Versatile Ingredients: You can easily substitute ingredients based on what you have on hand. Swap in rotisserie chicken for faster prep or try different cheeses to mix things up.

Low-Carb Goodness: Enjoy a hearty meal that aligns with your dietary preferences without sacrificing taste—this dish maintains a delightful taste experience while keeping carbs low.

Make-Ahead Convenience: Prepare this casserole in advance and pop it into the oven when you're ready, making it a lifesaver for meal prep and entertaining!

Chicken Spinach and Mushroom Low-Carb Casserole Ingredients

For the Casserole
• Thin-Sliced Chicken Breasts – A lean protein source for this low-carb chicken casserole; substitute with rotisserie chicken to save prep time.
• Green Onion Cream Cheese – Adds creaminess and flavor to the casserole; a dairy-free alternative can easily be used.
• Olive Oil – Perfect for sautéing, bringing richness to the dish; it can be swapped with avocado oil for a unique flavor twist.
• Chicken Broth – This provides moisture and a savory base, whether homemade or store-bought.
• Sliced Mushrooms – Contributes amazing umami and texture; use any variety you like!
• Fresh Baby Spinach – A nutrient-rich leafy green that elevates the dish; frozen spinach can work as a quick substitute—just thaw and squeeze out excess water.
• Weber Herb and Garlic Seasoning – This enhances flavor with a delightful blend of herbs and spices; use a blend of your favorite dried herbs if you don’t have this on hand.
• Shredded Mozzarella Cheese – Melts beautifully to create a cheesy topping; feel free to replace it with other cheeses for different tastes.
• Salt and Pepper – Essential basics, season to your liking!

This Chicken Spinach and Mushroom Low-Carb Casserole is not only easy and delicious, but it's also perfect for satisfying cravings while keeping things healthy!

How to Make Chicken Spinach and Mushroom Low-Carb Casserole

Preheat the oven to 375°F (190°C) and lightly grease a 13x9-inch baking dish. This prepares the perfect environment for your casserole to cook thoroughly and develop a golden, bubbly top.
Arrange the thin-sliced chicken breasts in a single layer in the baking dish. Sprinkle them generously with salt, pepper, and Weber Herb and Garlic Seasoning to enhance the flavors beautifully.
Sauté the sliced mushrooms in olive oil over medium heat until they become soft and fragrant, about 5 minutes. This step brings out their natural umami flavor, enriching the casserole.
Layer the sautéed mushrooms and fresh spinach evenly over the seasoned chicken in the baking dish. The vibrant greens will add nutrients and a pop of color to the dish.
Mix the green onion cream cheese, chicken broth, and a splash of olive oil in a bowl until smooth. This creamy mixture will bind all the ingredients together deliciously.
Pour the creamy mixture evenly over the chicken, mushrooms, and spinach, ensuring everything is well-coated. This will give each bite that comforting, creamy consistency.
Cover the baking dish loosely with foil and bake for 20 minutes. This initial baking phase helps the chicken cook thoroughly and allows the flavors to meld.
Remove the foil and continue baking for another 20 minutes. This will allow the top to firm up and start turning golden brown.
Top the casserole with shredded mozzarella cheese and return it to the oven for an additional 5-10 minutes until the cheese is melted and bubbly. The cheese adds that irresistible finishing touch!
Serve hot and enjoy the comforting flavors of this delicious casserole. It’s best shared with loved ones for an unforgettable meal experience!

Optional: Pair with a side of mixed greens for a refreshing crunch.

Exact quantities are listed in the recipe card below.

Chicken Spinach and Mushroom Low-Carb Casserole Variations

Feel free to let your creativity shine by customizing this delicious casserole to suit your taste!

Rotisserie Chicken: Use shredded rotisserie chicken for a quicker cooking time and even more flavor. It’s a great shortcut on busy days!
Dairy-Free: Substitute green onion cream cheese with a dairy-free cream cheese alternative for a completely dairy-free meal. This maintains that creamy texture everyone loves.
Cheese Swap: Try swapping mozzarella with sharp cheddar or creamy gouda for a different cheesy flair. Each cheese brings its unique taste to the table!
Veggie Boost: Add in low-carb vegetables like zucchini or broccoli to increase nutrition and texture. A medley of colors brightens up the dish while providing extra crunch.
Herb Upgrade: Swap Weber Herb and Garlic Seasoning with fresh herbs like thyme or rosemary for a more aromatic flavor profile. Fresh herbs can elevate the dish in a wonderful way!
Spicy Kick: Toss in some red pepper flakes to add a little heat to the casserole. Just a pinch can lift the flavors and set taste buds dancing!
Nutty Crunch: Consider topping your casserole with toasted almond slivers or breadcrumbs for a delightful crunch. It adds a fun texture contrast to the creamy base.
Savory Swap: Experiment with sautéed leeks or shallots instead of green onions for a deeper, richer flavor. It’s a simple change that makes a big difference!

What to Serve with Chicken Spinach and Mushroom Low-Carb Casserole?

Elevate your mealtime experience with vibrant sides that complement the creamy goodness of this casserole.

Mixed Green Salad: A refreshing salad with crisp greens and tangy vinaigrette adds a delightful crunch to the soft casserole.
Garlic Parmesan Zoodles: The lightness of zucchini noodles infused with garlic and parmesan offers a perfect low-carb side that pairs effortlessly.
Roasted Brussels Sprouts: Their slightly nutty and caramelized flavor will contrast beautifully with the creamy texture of the casserole. Toss with olive oil and seasoning for an easy prep.
Cauliflower Rice: For a beautiful textural contrast, serve fluffy cauliflower rice flavored with herbs alongside the casserole, keeping it low-carb.
Steamed Asparagus: Tender asparagus drizzled with lemon enhances the meal with a zesty brightness that complements the rich casserole.
Herb-Infused Quinoa: A side of fluffy quinoa with fresh herbs can introduce a different flavor profile while maintaining a healthy balance on your plate.

Remember to pair with a glass of chilled white wine or sparkling water to bring out the best flavors in your comforting Chicken Spinach and Mushroom Low-Carb Casserole!

Storage Tips for Chicken Spinach and Mushroom Low-Carb Casserole

Fridge: Store the casserole in an airtight container for up to 4 days. Allow it to cool completely before sealing to maintain freshness.
Freezer: You can freeze the casserole for up to 3 months. Wrap tightly in foil or use a freezer-safe dish to prevent freezer burn.
Reheating: To reheat, thaw overnight in the fridge if frozen, and then bake at 350°F (175°C) until heated through. This keeps the creamy texture of the chicken spinach bake intact.
Make-Ahead: Assemble the casserole ahead of time, cover, and refrigerate before baking. Just pop it in the oven when you're ready to enjoy a delicious home-cooked meal!

Make Ahead Options

These Chicken Spinach and Mushroom Low-Carb Casserole ingredients are perfect for meal prep enthusiasts! You can prepare the casserole up to 24 hours in advance by assembling all components (except the cheese) in the baking dish, then cover it tightly with foil to refrigerate. The fresh spinach and mushrooms ensure that it stays vibrant and flavorful; just be sure to avoid over-sautéing the vegetables. When you're ready to bake, simply remove it from the fridge, add the shredded mozzarella cheese on top, and bake it as directed for a wonderfully comforting meal that feels like it was made fresh just for you! This way, you’ll save valuable time on busy weeknights without sacrificing quality or taste.

Expert Tips for Chicken Spinach and Mushroom Low-Carb Casserole

Check the Temperature: Ensure the chicken is cooked through; an internal temperature of 165°F (74°C) guarantees safety and tenderness.
Texture Matters: Avoid over-sautéing the mushrooms to keep their texture intact. Too much cooking can turn them mushy in the final casserole.
Prep Ahead: For easier weeknight dinners, assemble the casserole the night before and refrigerate it. Just pop it in the oven when you're ready!
Cheese Options: Experiment with different cheeses; swapping out mozzarella for cheddar or gouda can elevate the flavors of your low-carb chicken casserole.
Season Smart: Adjust the seasoning according to your tastebuds. A pinch of salt and pepper can go a long way, ensuring the dish is perfectly seasoned.

Chicken Spinach and Mushroom Low-Carb Casserole Recipe FAQs

What type of chicken is best for this casserole?
Absolutely! I recommend using thin-sliced chicken breasts for their quick cooking time and lean protein. However, you can also substitute with rotisserie chicken to save prep time, just shred it and layer it in with the other ingredients.

How should I store leftover casserole?
Let your Chicken Spinach and Mushroom Low-Carb Casserole cool completely before transferring it to an airtight container. It will stay fresh in the fridge for up to 4 days. Just make sure to seal it properly to keep that creamy goodness intact!

Can I freeze the casserole, and if so, how?
Very! To freeze, wrap the casserole tightly in foil or use a properly sealed freezer-safe dish. This will prevent freezer burn and keep your casserole fresh for up to 3 months. When you're ready to enjoy it, thaw in the fridge overnight and then reheat at 350°F (175°C) until heated through.

What if I want to add more vegetables?
The more the merrier! Feel free to boost nutrition by adding low-carb veggies like zucchini or broccoli. You can layer them in with the mushrooms and spinach. Just make sure to sauté them briefly to remove excess moisture and keep the casserole from becoming too watery.

Can I make this dish dairy-free?
Absolutely! Simply substitute the green onion cream cheese with a dairy-free alternative, and choose a dairy-free cheese for the topping. You can also add some nutritional yeast for a cheesy flavor without the dairy.

How do I know if the chicken is cooked through?
To ensure the chicken in your casserole is cooked to perfection, use a meat thermometer to check for an internal temperature of 165°F (74°C). This not only guarantees the chicken is safe to eat but also ensures it's juicy and tender.